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A novel TGF-β receptor II mutation (I227T/N236D) promotes aggressive phenotype of oral squamous cell carcinoma via enhanced EGFR signaling

BACKGROUND: Transforming growth factor-β (TGF-β) signaling is a double-edged sword in cancer development and progression. TGF-β signaling plays a tumor suppressive role during the early stages of tumor development but promotes tumor progression in later stages. We have previously identified various...

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Detalles Bibliográficos
Autores principales:	Son, Hwa-Kyung, Kim, Dokyeong, Lim, Yongwoon, Kim, Jin, Park, Iha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694911/ https://www.ncbi.nlm.nih.gov/pubmed/33246423 http://dx.doi.org/10.1186/s12885-020-07669-5

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