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Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divide...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695027/ https://www.ncbi.nlm.nih.gov/pubmed/33171716 http://dx.doi.org/10.3390/jcm9113588 |
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author | Park, Ik Hyun Yang, Jeong Hoon Jang, Woo Jin Chun, Woo Jung Oh, Ju Hyeon Park, Yong Hwan Yu, Cheol Woong Kim, Hyun-Joong Kim, Bum Sung Jeong, Jin-Ok Lee, Hyun Jong Gwon, Hyeon-Cheol |
author_facet | Park, Ik Hyun Yang, Jeong Hoon Jang, Woo Jin Chun, Woo Jung Oh, Ju Hyeon Park, Yong Hwan Yu, Cheol Woong Kim, Hyun-Joong Kim, Bum Sung Jeong, Jin-Ok Lee, Hyun Jong Gwon, Hyeon-Cheol |
author_sort | Park, Ik Hyun |
collection | PubMed |
description | Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divided into two groups: patients undergoing extracorporeal membrane oxygenation as an adjunct to standard cardiopulmonary resuscitation for less than 38 min (n = 110) or for longer than 38 min (n = 73). The ECPR ≤ 38 min group had a significantly greater incidence of survival to discharge compared to the ECPR > 38 min group (40.0% versus 24.7%, p = 0.032). The incidence of good neurologic outcomes at discharge tended to be greater in the ECPR ≤ 38 min group than in the ECPR > 38 min group (35.5% versus 24.7%, p = 0.102). The incidences of limb ischemia (p = 0.354) and stroke (p = 0.805) were similar between the two groups, but major bleeding occurred less frequently in the ECPR ≤ 38 min group compared to the ECPR > 38 min group (p = 0.002). Low-flow time ≤ 38 min may reduce the risk of mortality and fatal neurologic damage and could be a measure of optimal management in patients with IHCA. |
format | Online Article Text |
id | pubmed-7695027 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76950272020-11-28 Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry Park, Ik Hyun Yang, Jeong Hoon Jang, Woo Jin Chun, Woo Jung Oh, Ju Hyeon Park, Yong Hwan Yu, Cheol Woong Kim, Hyun-Joong Kim, Bum Sung Jeong, Jin-Ok Lee, Hyun Jong Gwon, Hyeon-Cheol J Clin Med Article Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divided into two groups: patients undergoing extracorporeal membrane oxygenation as an adjunct to standard cardiopulmonary resuscitation for less than 38 min (n = 110) or for longer than 38 min (n = 73). The ECPR ≤ 38 min group had a significantly greater incidence of survival to discharge compared to the ECPR > 38 min group (40.0% versus 24.7%, p = 0.032). The incidence of good neurologic outcomes at discharge tended to be greater in the ECPR ≤ 38 min group than in the ECPR > 38 min group (35.5% versus 24.7%, p = 0.102). The incidences of limb ischemia (p = 0.354) and stroke (p = 0.805) were similar between the two groups, but major bleeding occurred less frequently in the ECPR ≤ 38 min group compared to the ECPR > 38 min group (p = 0.002). Low-flow time ≤ 38 min may reduce the risk of mortality and fatal neurologic damage and could be a measure of optimal management in patients with IHCA. MDPI 2020-11-07 /pmc/articles/PMC7695027/ /pubmed/33171716 http://dx.doi.org/10.3390/jcm9113588 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Park, Ik Hyun Yang, Jeong Hoon Jang, Woo Jin Chun, Woo Jung Oh, Ju Hyeon Park, Yong Hwan Yu, Cheol Woong Kim, Hyun-Joong Kim, Bum Sung Jeong, Jin-Ok Lee, Hyun Jong Gwon, Hyeon-Cheol Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry |
title | Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry |
title_full | Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry |
title_fullStr | Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry |
title_full_unstemmed | Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry |
title_short | Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry |
title_sort | clinical significance of low-flow time in patients undergoing extracorporeal cardiopulmonary resuscitation: results from the rescue registry |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695027/ https://www.ncbi.nlm.nih.gov/pubmed/33171716 http://dx.doi.org/10.3390/jcm9113588 |
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