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Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry

Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divide...

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Autores principales: Park, Ik Hyun, Yang, Jeong Hoon, Jang, Woo Jin, Chun, Woo Jung, Oh, Ju Hyeon, Park, Yong Hwan, Yu, Cheol Woong, Kim, Hyun-Joong, Kim, Bum Sung, Jeong, Jin-Ok, Lee, Hyun Jong, Gwon, Hyeon-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695027/
https://www.ncbi.nlm.nih.gov/pubmed/33171716
http://dx.doi.org/10.3390/jcm9113588
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author Park, Ik Hyun
Yang, Jeong Hoon
Jang, Woo Jin
Chun, Woo Jung
Oh, Ju Hyeon
Park, Yong Hwan
Yu, Cheol Woong
Kim, Hyun-Joong
Kim, Bum Sung
Jeong, Jin-Ok
Lee, Hyun Jong
Gwon, Hyeon-Cheol
author_facet Park, Ik Hyun
Yang, Jeong Hoon
Jang, Woo Jin
Chun, Woo Jung
Oh, Ju Hyeon
Park, Yong Hwan
Yu, Cheol Woong
Kim, Hyun-Joong
Kim, Bum Sung
Jeong, Jin-Ok
Lee, Hyun Jong
Gwon, Hyeon-Cheol
author_sort Park, Ik Hyun
collection PubMed
description Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divided into two groups: patients undergoing extracorporeal membrane oxygenation as an adjunct to standard cardiopulmonary resuscitation for less than 38 min (n = 110) or for longer than 38 min (n = 73). The ECPR ≤ 38 min group had a significantly greater incidence of survival to discharge compared to the ECPR > 38 min group (40.0% versus 24.7%, p = 0.032). The incidence of good neurologic outcomes at discharge tended to be greater in the ECPR ≤ 38 min group than in the ECPR > 38 min group (35.5% versus 24.7%, p = 0.102). The incidences of limb ischemia (p = 0.354) and stroke (p = 0.805) were similar between the two groups, but major bleeding occurred less frequently in the ECPR ≤ 38 min group compared to the ECPR > 38 min group (p = 0.002). Low-flow time ≤ 38 min may reduce the risk of mortality and fatal neurologic damage and could be a measure of optimal management in patients with IHCA.
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spelling pubmed-76950272020-11-28 Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry Park, Ik Hyun Yang, Jeong Hoon Jang, Woo Jin Chun, Woo Jung Oh, Ju Hyeon Park, Yong Hwan Yu, Cheol Woong Kim, Hyun-Joong Kim, Bum Sung Jeong, Jin-Ok Lee, Hyun Jong Gwon, Hyeon-Cheol J Clin Med Article Limited data are available on the association between low-flow time and survival in patients with in-hospital cardiac arrest (IHCA) who undergo extracorporeal cardiopulmonary resuscitation (ECPR). We evaluated data from 183 IHCA patients who underwent ECPR as a rescue procedure. Patients were divided into two groups: patients undergoing extracorporeal membrane oxygenation as an adjunct to standard cardiopulmonary resuscitation for less than 38 min (n = 110) or for longer than 38 min (n = 73). The ECPR ≤ 38 min group had a significantly greater incidence of survival to discharge compared to the ECPR > 38 min group (40.0% versus 24.7%, p = 0.032). The incidence of good neurologic outcomes at discharge tended to be greater in the ECPR ≤ 38 min group than in the ECPR > 38 min group (35.5% versus 24.7%, p = 0.102). The incidences of limb ischemia (p = 0.354) and stroke (p = 0.805) were similar between the two groups, but major bleeding occurred less frequently in the ECPR ≤ 38 min group compared to the ECPR > 38 min group (p = 0.002). Low-flow time ≤ 38 min may reduce the risk of mortality and fatal neurologic damage and could be a measure of optimal management in patients with IHCA. MDPI 2020-11-07 /pmc/articles/PMC7695027/ /pubmed/33171716 http://dx.doi.org/10.3390/jcm9113588 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Ik Hyun
Yang, Jeong Hoon
Jang, Woo Jin
Chun, Woo Jung
Oh, Ju Hyeon
Park, Yong Hwan
Yu, Cheol Woong
Kim, Hyun-Joong
Kim, Bum Sung
Jeong, Jin-Ok
Lee, Hyun Jong
Gwon, Hyeon-Cheol
Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
title Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
title_full Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
title_fullStr Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
title_full_unstemmed Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
title_short Clinical Significance of Low-Flow Time in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: Results from the RESCUE Registry
title_sort clinical significance of low-flow time in patients undergoing extracorporeal cardiopulmonary resuscitation: results from the rescue registry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695027/
https://www.ncbi.nlm.nih.gov/pubmed/33171716
http://dx.doi.org/10.3390/jcm9113588
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