Small RNA Plays Important Roles in Virus–Host Interactions

Non-coding small RNAs play important roles in virus–host interactions. For hosts, small RNAs can serve as sensors in antiviral pathways including RNAi and CRISPR; for viruses, small RNAs can be involved in viral transcription and replication. This paper covers several recent discoveries on small RNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Hui, Gu, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695165/
https://www.ncbi.nlm.nih.gov/pubmed/33171824
http://dx.doi.org/10.3390/v12111271
_version_ 1783615127667343360
author Dai, Hui
Gu, Weifeng
author_facet Dai, Hui
Gu, Weifeng
author_sort Dai, Hui
collection PubMed
description Non-coding small RNAs play important roles in virus–host interactions. For hosts, small RNAs can serve as sensors in antiviral pathways including RNAi and CRISPR; for viruses, small RNAs can be involved in viral transcription and replication. This paper covers several recent discoveries on small RNA mediated virus–host interactions, and focuses on influenza virus cap-snatching and a few important virus sensors including PIR-1, RIG-I like protein DRH-1 and piRNAs. The paper also discusses recent advances in mammalian antiviral RNAi.
format Online
Article
Text
id pubmed-7695165
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-76951652020-11-28 Small RNA Plays Important Roles in Virus–Host Interactions Dai, Hui Gu, Weifeng Viruses Review Non-coding small RNAs play important roles in virus–host interactions. For hosts, small RNAs can serve as sensors in antiviral pathways including RNAi and CRISPR; for viruses, small RNAs can be involved in viral transcription and replication. This paper covers several recent discoveries on small RNA mediated virus–host interactions, and focuses on influenza virus cap-snatching and a few important virus sensors including PIR-1, RIG-I like protein DRH-1 and piRNAs. The paper also discusses recent advances in mammalian antiviral RNAi. MDPI 2020-11-07 /pmc/articles/PMC7695165/ /pubmed/33171824 http://dx.doi.org/10.3390/v12111271 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dai, Hui
Gu, Weifeng
Small RNA Plays Important Roles in Virus–Host Interactions
title Small RNA Plays Important Roles in Virus–Host Interactions
title_full Small RNA Plays Important Roles in Virus–Host Interactions
title_fullStr Small RNA Plays Important Roles in Virus–Host Interactions
title_full_unstemmed Small RNA Plays Important Roles in Virus–Host Interactions
title_short Small RNA Plays Important Roles in Virus–Host Interactions
title_sort small rna plays important roles in virus–host interactions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695165/
https://www.ncbi.nlm.nih.gov/pubmed/33171824
http://dx.doi.org/10.3390/v12111271
work_keys_str_mv AT daihui smallrnaplaysimportantrolesinvirushostinteractions
AT guweifeng smallrnaplaysimportantrolesinvirushostinteractions

Ejemplares similares