Cargando…
Targeting the Interaction between the SH3 Domain of Grb2 and Gab2
Gab2 is a scaffolding protein, overexpressed in many types of cancers, that plays a key role in the formation of signaling complexes involved in cellular proliferation, migration, and differentiation. The interaction between Gab2 and the C-terminal SH3 domain of the protein Grb2 is crucial for the a...
Autores principales: | Malagrinò, Francesca, Coluccia, Antonio, Bufano, Marianna, Regina, Giuseppe La, Puxeddu, Michela, Toto, Angelo, Visconti, Lorenzo, Paone, Alessio, Magnifico, Maria Chiara, Troilo, Francesca, Cutruzzolà, Francesca, Silvestri, Romano, Gianni, Stefano |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695167/ https://www.ncbi.nlm.nih.gov/pubmed/33171874 http://dx.doi.org/10.3390/cells9112435 |
Ejemplares similares
-
Understanding the Mechanism of Recognition of Gab2 by the N-SH2 Domain of SHP2
por: Visconti, Lorenzo, et al.
Publicado: (2020) -
The Effect of Proline cis-trans Isomerization on the Folding of the C-Terminal SH2 Domain from p85
por: Troilo, Francesca, et al.
Publicado: (2019) -
Demonstration of Binding Induced Structural Plasticity in a SH2 Domain
por: Visconti, Lorenzo, et al.
Publicado: (2020) -
Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2
por: Toto, Angelo, et al.
Publicado: (2017) -
Mapping the allosteric network within a SH3 domain
por: Malagrinò, Francesca, et al.
Publicado: (2019)