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Characterization of UVA-Induced Alterations to Transfer RNA Sequences

Ultraviolet radiation (UVR) adversely affects the integrity of DNA, RNA, and their nucleoside modifications. By employing liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based RNA modification mapping approaches, we identified the transfer RNA (tRNA) regions most vulnerable to photooxidati...

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Detalles Bibliográficos
Autores principales: Sun, Congliang, Limbach, Patrick A., Addepalli, Balasubrahmanyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695249/
https://www.ncbi.nlm.nih.gov/pubmed/33171700
http://dx.doi.org/10.3390/biom10111527