Structural Insight into Integrin Recognition and Anticancer Activity of Echistatin

Echistatin (Ech) is a short disintegrin with a long (42)NPHKGPAT C-terminal tail. We determined the 3-D structure of Ech by X-ray crystallography. Superimposition of the structures of chains A and B showed conformational differences in their RGD loops and C-termini. The chain A structure is consiste...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Chun, Chang, Yao-Tsung, Chen, Chiu-Yueh, Shiu, Jia-Hau, Cheng, Chun-Ho, Huang, Chun-Hao, Chen, Ju-Fei, Chuang, Woei-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695343/
https://www.ncbi.nlm.nih.gov/pubmed/33182321
http://dx.doi.org/10.3390/toxins12110709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695343/
https://www.ncbi.nlm.nih.gov/pubmed/33182321
http://dx.doi.org/10.3390/toxins12110709

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