Cargando…

CircGLCE alleviates intervertebral disc degeneration by regulating apoptosis and matrix degradation through the targeting of miR-587/STAP1

The purpose of this study was to identify a specific circular RNA and to investigate its regulatory mechanism in intervertebral disc degeneration (IDD). CircGLCE was selected after microarray analyses and was further analysed by RT-qPCR and FISH. CircGLCE was found to stably exist in the cytoplasm o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zhonghui, Zhang, Weibing, Deng, Ming, Li, Yaming, Zhou, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695369/ https://www.ncbi.nlm.nih.gov/pubmed/33159017 http://dx.doi.org/10.18632/aging.104035

Ejemplares similares

Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo
por: Wang, Hao, et al.
Publicado: (2020)

The Roles of circRNAs in Intervertebral Disc Degeneration: Inflammation, Extracellular Matrix Metabolism, and Apoptosis
por: Li, Hao, et al.
Publicado: (2022)

Down‐regulation of insulin‐like growth factor binding protein 5 is involved in intervertebral disc degeneration via the ERK signalling pathway
por: Chen, Zhonghui, et al.
Publicado: (2019)

The pathological mechanisms of circRNAs in mediating intervertebral disc degeneration
por: Li, Yongjin, et al.
Publicado: (2023)

Extracellular matrix remodeling in experimental intervertebral disc degeneration
por: de Oliveira, Cintia Pereira, et al.
Publicado: (2013)

Senolytics: Eliminating Senescent Cells and Alleviating Intervertebral Disc Degeneration
por: Wu, Yuhao, et al.
Publicado: (2022)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

CircRNA expression profile and potential role of hsa_circ_0040039 in intervertebral disc degeneration
por: Huang, Sheng, et al.
Publicado: (2022)

Importance of Matrix Cues on Intervertebral Disc Development, Degeneration, and Regeneration
por: Kibble, Matthew J., et al.
Publicado: (2022)

Sal003 alleviated intervertebral disc degeneration by inhibiting apoptosis and extracellular matrix degradation through suppressing endoplasmic reticulum stress pathway in rats
por: Chen, Yan, et al.
Publicado: (2023)

Prognostic value of GLCE and infiltrating immune cells in Ewing sarcoma
por: Wen, Jian, et al.
Publicado: (2023)

Circ_0005918 Sponges miR-622 to Aggravate Intervertebral Disc Degeneration
por: Cui, Yan, et al.
Publicado: (2022)

Matrix Degradative Enzymes and Their Inhibitors during Annular Inflammation: Initial Step of Symptomatic Intervertebral Disc Degeneration
por: Kim, Joo Han, et al.
Publicado: (2014)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Macrophages and Intervertebral Disc Degeneration
por: Koroth, Jinsha, et al.
Publicado: (2023)

Overexpression of miR-148a-3p inhibits extracellular matrix degradation and alleviates IL-1β-induced intervertebral disc degeneration
por: Lai, Hehuan, et al.
Publicado: (2023)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

Tetrandrine reduces oxidative stress, apoptosis, and extracellular matrix degradation and improves intervertebral disc degeneration by inducing autophagy
por: Liu, Jintao, et al.
Publicado: (2022)

How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration
por: Zhang, Qing-Xiang, et al.
Publicado: (2023)

DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis
por: Luo, Zhiqiang, et al.
Publicado: (2021)

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Cordycepin inhibits LPS-induced inflammatory and matrix degradation in the intervertebral disc
por: Li, Yan, et al.
Publicado: (2016)

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration
por: Munir, Sabrina, et al.
Publicado: (2018)

Angiogenesis in the degeneration of the lumbar intervertebral disc
por: David, Gh, et al.
Publicado: (2010)

Intervertebral disc degeneration therapies in human
por: Richardson, Stephen M
Publicado: (2015)

Genetic factors in intervertebral disc degeneration
por: Feng, Yi, et al.
Publicado: (2016)

The Role of Adipokines in Intervertebral Disc Degeneration
por: Sharma, Anirudh
Publicado: (2018)

Molecular Mechanisms of Intervertebral Disc Degeneration
por: Rider, Sean M., et al.
Publicado: (2018)

Genetic Therapy for Intervertebral Disc Degeneration
por: Roh, Eun Ji, et al.
Publicado: (2021)

Cervical intervertebral disc degeneration and dizziness
por: Liu, Tang-Hua, et al.
Publicado: (2021)

The Proteolysis of ECM in Intervertebral Disc Degeneration
por: Liang, Huaizhen, et al.
Publicado: (2022)

The role of ferroptosis in intervertebral disc degeneration
por: Fan, Chunyang, et al.
Publicado: (2023)

Role of Necroptosis in Intervertebral Disc Degeneration
por: Khaleque, Md Abdul, et al.
Publicado: (2023)

Hsa_circ_0134111 promotes intervertebral disc degeneration via sponging miR-578
por: Yan, Peng, et al.
Publicado: (2022)

Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy
por: Zhang, Shuwen, et al.
Publicado: (2021)

Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction
por: Dai, Zhanqiu, et al.
Publicado: (2022)

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
por: Millward-Sadler, S Jane, et al.
Publicado: (2009)

Circ-RNA Expression Pattern and circ-RNA-miRNA-mRNA Network in The Pathogenesis of Human Intervertebral Disc Degeneration
por: Guo, Zhiliang, et al.
Publicado: (2021)

Circular RNA ITCH promotes extracellular matrix degradation via activating Wnt/β-catenin signaling in intervertebral disc degeneration
por: Zhang, Feng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2884bti427cjqunfskq1mdrcan