Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure

In this study, we studied the effect and possible mechanism of TGF-β1 on vascular calcification. We found that the serum levels of TGF-β1 and cycloxygenase-2 (COX-2) were significantly increased in patients with chronic kidney disease. Phosphate up regulated TGF-β1 in vascular smooth muscle cells (V...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Fang, Li, Ling, Li, Pei-Pei, Deng, Yan, Yang, Yuan-Yuan, Deng, Yi-Xuan, Luo, Hong-Hong, Yao, Xin-Tong, Su, Yu-Xi, Gan, Hua, He, Bai-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695383/
https://www.ncbi.nlm.nih.gov/pubmed/33159018
http://dx.doi.org/10.18632/aging.103827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695383/
https://www.ncbi.nlm.nih.gov/pubmed/33159018
http://dx.doi.org/10.18632/aging.103827

Ejemplares similares