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Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure

In this study, we studied the effect and possible mechanism of TGF-β1 on vascular calcification. We found that the serum levels of TGF-β1 and cycloxygenase-2 (COX-2) were significantly increased in patients with chronic kidney disease. Phosphate up regulated TGF-β1 in vascular smooth muscle cells (V...

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Detalles Bibliográficos
Autores principales:	He, Fang, Li, Ling, Li, Pei-Pei, Deng, Yan, Yang, Yuan-Yuan, Deng, Yi-Xuan, Luo, Hong-Hong, Yao, Xin-Tong, Su, Yu-Xi, Gan, Hua, He, Bai-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695383/ https://www.ncbi.nlm.nih.gov/pubmed/33159018 http://dx.doi.org/10.18632/aging.103827

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