High phosphate induces skeletal muscle atrophy and suppresses myogenic differentiation by increasing oxidative stress and activating Nrf2 signaling

Skeletal muscle wasting represents both a common phenotype of aging and a feature of pathological conditions such as chronic kidney disease (CKD). Although both clinical data and genetic experiments in mice suggest that hyperphosphatemia accelerates muscle wasting, the underlying mechanism remains u...

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Detalles Bibliográficos
Autores principales: Chung, Lin-Huei, Liu, Shu-Ting, Huang, Shih-Ming, Salter, Donald M., Lee, Herng-Sheng, Hsu, Yu-Juei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695395/
https://www.ncbi.nlm.nih.gov/pubmed/33136552
http://dx.doi.org/10.18632/aging.103896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695395/
https://www.ncbi.nlm.nih.gov/pubmed/33136552
http://dx.doi.org/10.18632/aging.103896

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