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Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro

Naked mole-rats are extraordinarily long-lived rodents that offer unique opportunities to study the molecular origins of age-related neurodegenerative diseases. Remarkably, they do not accumulate amyloid plaques, even though their brains contain high concentrations of amyloid beta (Aβ) peptide from...

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Detalles Bibliográficos
Autores principales: Frankel, Daniel, Davies, Matthew, Bhushan, Bharat, Kulaberoglu, Yavuz, Urriola-Munoz, Paulina, Bertrand-Michel, Justine, Pergande, Melissa R., Smith, Andrew A., Preet, Swapan, Park, Thomas J., Vendruscolo, Michele, Rankin, Kenneth S., Cologna, Stephanie M., Kumita, Janet R., Cenac, Nicolas, St John Smith, Ewan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695401/
https://www.ncbi.nlm.nih.gov/pubmed/33147569
http://dx.doi.org/10.18632/aging.202138