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Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro
Naked mole-rats are extraordinarily long-lived rodents that offer unique opportunities to study the molecular origins of age-related neurodegenerative diseases. Remarkably, they do not accumulate amyloid plaques, even though their brains contain high concentrations of amyloid beta (Aβ) peptide from...
Autores principales: | Frankel, Daniel, Davies, Matthew, Bhushan, Bharat, Kulaberoglu, Yavuz, Urriola-Munoz, Paulina, Bertrand-Michel, Justine, Pergande, Melissa R., Smith, Andrew A., Preet, Swapan, Park, Thomas J., Vendruscolo, Michele, Rankin, Kenneth S., Cologna, Stephanie M., Kumita, Janet R., Cenac, Nicolas, St John Smith, Ewan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695401/ https://www.ncbi.nlm.nih.gov/pubmed/33147569 http://dx.doi.org/10.18632/aging.202138 |
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