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IGF2 loss of imprinting enhances colorectal cancer stem cells pluripotency by promoting tumor autophagy
Cancer stem cells (CSCs) are believed to be the driving force behind the tumor growth. We performed this study to further explore the role of IGF2 epigenetic on CRC stem cells pluripotency which showed that IGF2 LOI CRC cells usually had a higher CD133 expression and sphere forming efficiency than M...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695407/ https://www.ncbi.nlm.nih.gov/pubmed/33173015 http://dx.doi.org/10.18632/aging.103837 |