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Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging

Vascular endothelial cell senescence and endoplasmic reticulum (ER) stress induced unfolded protein response (UPR) are two critical contributors to individual aging. However, whether these two biological events have crosstalk and are controlled by shared upstream regulators are largely unknown. Here...

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Detalles Bibliográficos
Autores principales: Yang, Di, Wang, Qing, Wei, Gang, Wu, Jiaxue, Zhu, Yi Chun, Zhu, Qing, Ni, Ting, Liu, Xinhua, Zhu, Yi Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695420/
https://www.ncbi.nlm.nih.gov/pubmed/33144524
http://dx.doi.org/10.18632/aging.103895