16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

Microdeletions and microduplications of the 16p11.2 chromosomal locus are associated with syndromic neurodevelopmental disorders and reciprocal physiological conditions such as macro/microcephaly and high/low body mass index. To facilitate cellular and molecular investigations into these phenotypes,...

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Detalles Bibliográficos
Autores principales: Roth, Julien G, Muench, Kristin L, Asokan, Aditya, Mallett, Victoria M, Gai, Hui, Verma, Yogendra, Weber, Stephen, Charlton, Carol, Fowler, Jonas L, Loh, Kyle M, Dolmetsch, Ricardo E, Palmer, Theo D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695459/
https://www.ncbi.nlm.nih.gov/pubmed/33169669
http://dx.doi.org/10.7554/eLife.58178

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