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Serotonergic projections to the orbitofrontal and medial prefrontal cortices differentially modulate waiting for future rewards

Optogenetic activation of serotonergic neurons in the dorsal raphe nucleus (DRN) enhances patience when waiting for future rewards, and this effect is maximized by both high probability and high timing uncertainty of reward. Here, we explored which serotonin projection areas contribute to these effe...

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Detalles Bibliográficos
Autores principales: Miyazaki, Katsuhiko, Miyazaki, Kayoko W., Sivori, Gaston, Yamanaka, Akihiro, Tanaka, Kenji F., Doya, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695476/
https://www.ncbi.nlm.nih.gov/pubmed/33246957
http://dx.doi.org/10.1126/sciadv.abc7246