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Thermal inactivation scaling applied for SARS-CoV-2

Based on a model of protein denaturation rate limited by an entropy-related barrier, we derive a simple formula for virus inactivation time as a function of temperature. Loss of protein structure is described by two reaction coordinates: conformational disorder of the polymer and wetting by the solv...

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Detalles Bibliográficos
Autores principales: Seifer, Shahar, Elbaum, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695547/
https://www.ncbi.nlm.nih.gov/pubmed/33253633
http://dx.doi.org/10.1016/j.bpj.2020.11.2259