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ADAMTS‐13 and bleeding phenotype in von Willebrand disease

BACKGROUND: The bleeding phenotype of von Willebrand disease (VWD) varies highly between patients and can only partly be explained by von Willebrand factor (VWF) parameters. By cleaving large VWF multimers into smaller, less active multimers, ADAMTS‐13 is an important regulator of VWF activity. Howe...

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Detalles Bibliográficos
Autores principales: Boender, Johan, Nederlof, Angelique, Meijer, Karina, Mauser‐Bunschoten, Evelien P., Cnossen, Marjon H., Fijnvandraat, Karin, van der Bom, Johanna G., de Meris, Joke, Laros‐van Gorkom, Britta A. P., van Galen, Karin P. M., Eikenboom, Jeroen, de Maat, Moniek P. M, Leebeek, Frank W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695560/
https://www.ncbi.nlm.nih.gov/pubmed/33313472
http://dx.doi.org/10.1002/rth2.12442