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Remdesivir Is Effective in Combating COVID-19 because It Is a Better Substrate than ATP for the Viral RNA-Dependent RNA Polymerase

COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is currently being treated using Remdesivir, a nucleoside analog that inhibits the RNA-dependent-RNA polymerase (RdRp). However, the enzymatic mechanism and efficiency of Remdesivir have not been determined, a...

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Detalles Bibliográficos
Autores principales:	Dangerfield, Tyler L., Huang, Nathan Z., Johnson, Kenneth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695572/ https://www.ncbi.nlm.nih.gov/pubmed/33283177 http://dx.doi.org/10.1016/j.isci.2020.101849

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