Cargando…

Tolperisone for the Treatment of Acute Muscle Spasm of the Back: Results from the Dose-Ranging Phase 2 STAR Study (NCT03802565)

OBJECTIVE: Use of skeletal muscle relaxants (SMRs) for acute muscle spasm is confounded by central nervous system adverse events (AEs), including somnolence. Tolperisone is an SMR that does not appear to be associated with somnolence. The aim of this study was to assess the safety and efficacy of to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nalamachu, Srinivas, Pergolizzi, Joseph, Kaye, Randall
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695600/ https://www.ncbi.nlm.nih.gov/pubmed/33262641 http://dx.doi.org/10.2147/JPR.S278857

Ejemplares similares

An assessment of the centrally acting muscle relaxant tolperisone on driving ability and cognitive effects compared to placebo and cyclobenzaprine
por: Caron, Judy, et al.
Publicado: (2020)

Clinical Comparative Study: Efficacy and Tolerability of Tolperisone and Thiocolchicoside in Acute Low Back Pain and Spinal Muscle Spasticity
por: Rao, Rajeev, et al.
Publicado: (2012)

Basic Aspects of the Pharmacodynamics of Tolperisone, A Widely Applicable Centrally Acting Muscle Relaxant
por: Tekes, Kornelia
Publicado: (2014)

Reversed phase-high performance liquid chromatographic method for simultaneous estimation of tolperisone hydrochloride and etodolac in a combined fixed dose oral formulations
por: Patel, Mit J., et al.
Publicado: (2011)

Development and Validation of a Precise, Single HPLC Method for the Determination of Tolperisone Impurities in API and Pharmaceutical Dosage Forms
por: Raju, Thummala Veera Raghava, et al.
Publicado: (2013)

The Acute Antiallodynic Effect of Tolperisone in Rat Neuropathic Pain and Evaluation of Its Mechanism of Action
por: Lakatos, Péter P., et al.
Publicado: (2022)

An Evaluation of Total Disintegration Time for Three Different Doses of Sublingual Fentanyl Tablets in Patients with Breakthrough Pain
por: Nalamachu, Srinivas
Publicado: (2013)

Pregabalin–Tolperisone Combination to Treat Neuropathic Pain: Improved Analgesia and Reduced Side Effects in Rats
por: Essmat, Nariman, et al.
Publicado: (2023)

The comparative study of clinical efficacy and safety of baclofen vs tolperisone in spasticity caused by spinal cord injury
por: Luo, Dejun, et al.
Publicado: (2017)

Screen-printed sensors for efficient potentiometric analysis of tolperisone hydrochloride in presence of its co-formulated drugs
por: Rizk, Mohamed, et al.
Publicado: (2022)

Spasm of the Eye Muscles
por: Chisolm, Julian J.
Publicado: (1881)

Fast-Acting Sublingual Zolpidem for Middle-of-the-Night Wakefulness
por: Pergolizzi, Joseph V., et al.
Publicado: (2014)

Development of Federally Mandated Risk Evaluation and Mitigation Strategies (REMS) for Transmucosal Immediate-Release Fentanyl Products
por: Pergolizzi, Joseph V, et al.
Publicado: (2013)

Sustainable Removal of Tolperisone from Waters by Application of Photocatalysis, Nanotechnology, and Chemometrics: Quantification, Environmental Toxicity, and Degradation Optimization
por: Bognár, Szabolcs, et al.
Publicado: (2022)

BALB.NCT-Cpox(nct) is a unique mouse model of hereditary coproporphyria
por: Kang, Xiaojing, et al.
Publicado: (2023)

Curious case of muscle spasm
por: Stratemeier, Natalie, et al.
Publicado: (2014)

Tramadol/Paracetamol Fixed-Dose Combination for Chronic Pain Management in Family Practice: A Clinical Review
por: Morón Merchante, Ignacio, et al.
Publicado: (2013)

Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain
por: Pergolizzi, Joseph V, et al.
Publicado: (2012)

Application of human factors engineering (HFE) to the design of a naloxone auto-injector for the treatment of opioid emergencies
por: Raffa, Robert B., et al.
Publicado: (2016)

Rationale, design, and protocol for the prevention of low back pain in the military (POLM) trial (NCT00373009)
por: George, Steven Z, et al.
Publicado: (2007)

Britain backs Beta Star
Publicado: (1970)

Effectiveness and gastrointestinal tolerability during conversion and titration with once-daily OROS® hydromorphone extended release in opioid-tolerant patients with chronic low back pain
por: Hale, Martin E, et al.
Publicado: (2013)

Chemometrics-Assisted UV Spectrophotometric and RP-HPLC Methods for the Simultaneous Determination of Tolperisone Hydrochloride and Diclofenac Sodium in their Combined Pharmaceutical Formulation
por: Gohel, Nikunj Rameshbhai, et al.
Publicado: (2013)

Masseteric muscle spasm following neostigmine
por: Bhaskar, S Bala, et al.
Publicado: (2012)

Masseter spasm after muscle relaxant
por: Raut, Monish S., et al.
Publicado: (2015)

Muscle Spasm and Light Touch Palpation
Publicado: (1913)

Clonic Spasm of the Muscles of the Eustachian Tube
Publicado: (1871)

Opioid rotation with extended-release opioids: where should we begin?
por: Nalamachu, Srinivas
Publicado: (2011)

Pharmacokinetics of Fentanyl Sublingual Spray in Opioid-Naïve Participants: Results of a Phase 1, Multiple Ascending Dose Study
por: Rauck, Richard L., et al.
Publicado: (2018)

The ischemic model of chronic muscle spasm and pain
por: Coletti, Roger H.
Publicado: (2022)

Efficacy and safety of tolperisone versus baclofen among Chinese patients with spasticity associated with spinal cord injury: a non-randomized retrospective study
por: Li, Mingheng, et al.
Publicado: (2021)

THE EFFECTS OF BACK EXTENSION TRAINING ON BACK MUSCLE STRENGTH AND SPINAL RANGE OF MOTION IN YOUNG FEMALES
por: Yaprak, Y.
Publicado: (2013)

Spasm of the Group of Muscles Supplied by the Musculo-Spiral Nerve
por: Jamieson, Wm. Allan
Publicado: (1869)

Nonspastic hemifacial spasm confirmed by abnormal muscle responses
por: Tani, Shigeru, et al.
Publicado: (2017)

Medical marijuana for the treatment of vismodegib-related muscle spasm
por: Yuan, Joyce T., et al.
Publicado: (2017)

Stretching the Facial Nerve for the Relief of Spasm of the Facial Muscles
Publicado: (1881)

Characteristics of Analgesic Patch Formulations
por: Nalamachu, Srinivas, et al.
Publicado: (2020)

Diagnosing and Managing Postherpetic Neuralgia
por: Nalamachu, Srinivas, et al.
Publicado: (2012)

Preoperative robotic radiosurgery for early breast cancer: Results of the phase II ROCK trial (NCT03520894)
por: Meattini, Icro, et al.
Publicado: (2022)

Safety and efficacy of sorafenib in patients with advanced thyroid carcinoma: a phase II study (NCT02084732)
por: Fierro-Maya, Luis Felipe, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d8sjorelh0sdo09smgphdlkj8a