Characterization of Anchorless Human PrP With Q227X Stop Mutation Linked to Gerstmann-Sträussler-Scheinker Syndrome In Vivo and In Vitro

Alteration in cellular prion protein (PrP(C)) localization on the cell surface through mediation of the glycosylphosphatidylinositol (GPI) anchor has been reported to dramatically affect the formation and infectivity of its pathological isoform (PrP(Sc)). A patient with Gerstmann-Sträussler-Scheinke...

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Detalles Bibliográficos
Autores principales: Shen, Pingping, Dang, Johnny, Wang, Zerui, Zhang, Weiguanliu, Yuan, Jue, Lang, Yue, Ding, Mingxuan, Mitchell, Marcus, Kong, Qingzhong, Feng, Jiachun, Rozemuller, Annemiek J. M., Cui, Li, Petersen, Robert B., Zou, Wen-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695670/
https://www.ncbi.nlm.nih.gov/pubmed/32889654
http://dx.doi.org/10.1007/s12035-020-02098-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695670/
https://www.ncbi.nlm.nih.gov/pubmed/32889654
http://dx.doi.org/10.1007/s12035-020-02098-8

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