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UAF1 deubiquitinase complexes facilitate NLRP3 inflammasome activation by promoting NLRP3 expression
NOD-like receptor protein 3 (NLRP3) detects microbial infections or endogenous danger signals and activates the NLRP3 inflammasome, which has important functions in host defense and contributes to the pathogenesis of inflammatory diseases, and thereby needs to be tightly controlled. Deubiquitination...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695691/ https://www.ncbi.nlm.nih.gov/pubmed/33247121 http://dx.doi.org/10.1038/s41467-020-19939-8 |