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A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis
Post-traumatic osteoarthritis (PTOA) is a major cause which hinders patients from the recovery after intra-articular injuries or surgeries. Currently, no effective treatment is available. In this study, we showed that inhibition of the acute stage chondrocyte death is a promising strategy to mitigat...
Autores principales: | Saito, Motoo, Nishitani, Kohei, Ikeda, Hanako O., Yoshida, Shigeo, Iwai, Sachiko, Ji, Xiang, Nakahata, Akihiro, Ito, Akira, Nakamura, Shinichiro, Kuriyama, Shinichi, Yoshitomi, Hiroyuki, Murata, Koichi, Aoyama, Tomoki, Ito, Hiromu, Kuroki, Hiroshi, Kakizuka, Akira, Matsuda, Shuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695735/ https://www.ncbi.nlm.nih.gov/pubmed/33247195 http://dx.doi.org/10.1038/s41598-020-77735-2 |
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