A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis

Post-traumatic osteoarthritis (PTOA) is a major cause which hinders patients from the recovery after intra-articular injuries or surgeries. Currently, no effective treatment is available. In this study, we showed that inhibition of the acute stage chondrocyte death is a promising strategy to mitigat...

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Detalles Bibliográficos
Autores principales: Saito, Motoo, Nishitani, Kohei, Ikeda, Hanako O., Yoshida, Shigeo, Iwai, Sachiko, Ji, Xiang, Nakahata, Akihiro, Ito, Akira, Nakamura, Shinichiro, Kuriyama, Shinichi, Yoshitomi, Hiroyuki, Murata, Koichi, Aoyama, Tomoki, Ito, Hiromu, Kuroki, Hiroshi, Kakizuka, Akira, Matsuda, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695735/
https://www.ncbi.nlm.nih.gov/pubmed/33247195
http://dx.doi.org/10.1038/s41598-020-77735-2

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