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Weak acids induce PGE(2) production in human oesophageal cells: novel mechanisms underlying GERD symptoms

The role of weak acids with pH values in the range of 4–7 has been implicated in the symptoms of gastroesophageal reflux disease (GERD). Prostaglandin E(2) (PGE(2)) is associated with heartburn symptom in GERD patients; however, the precise productive mechanisms remain unclear. In this study, we rev...

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Detalles Bibliográficos
Autores principales: Sadatomi, Daichi, Kono, Toru, Mogami, Sachiko, Fujitsuka, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695745/
https://www.ncbi.nlm.nih.gov/pubmed/33247192
http://dx.doi.org/10.1038/s41598-020-77495-z