Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting

Radionuclide molecular imaging of cancer-specific targets is a promising method to identify patients for targeted antibody therapy. Radiolabeled full-length antibodies however suffer from slow clearance, resulting in high background radiation. To overcome this problem, a pretargeting system based on...

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Detalles Bibliográficos
Autores principales: Myrhammar, Anders, Vorobyeva, Anzhelika, Westerlund, Kristina, Yoneoka, Shuichiro, Orlova, Anna, Tsukahara, Takehiko, Tolmachev, Vladimir, Karlström, Amelie Eriksson, Altai, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695838/
https://www.ncbi.nlm.nih.gov/pubmed/33247180
http://dx.doi.org/10.1038/s41598-020-77523-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695838/
https://www.ncbi.nlm.nih.gov/pubmed/33247180
http://dx.doi.org/10.1038/s41598-020-77523-y

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