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Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting
Radionuclide molecular imaging of cancer-specific targets is a promising method to identify patients for targeted antibody therapy. Radiolabeled full-length antibodies however suffer from slow clearance, resulting in high background radiation. To overcome this problem, a pretargeting system based on...
Autores principales: | Myrhammar, Anders, Vorobyeva, Anzhelika, Westerlund, Kristina, Yoneoka, Shuichiro, Orlova, Anna, Tsukahara, Takehiko, Tolmachev, Vladimir, Karlström, Amelie Eriksson, Altai, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695838/ https://www.ncbi.nlm.nih.gov/pubmed/33247180 http://dx.doi.org/10.1038/s41598-020-77523-y |
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