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Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells
Cadmium (Cd(2+)) is considered a human carcinogen as it causes oxidative stress and alters DNA repair responses. However, how Cd(2+) is taken up by cells remains unclear. We hypothesized that Cd(2+) could be transported into cells via a membrane copper (Cu) transporter, CTR1. CTR1 expression was not...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695923/ https://www.ncbi.nlm.nih.gov/pubmed/33294387 http://dx.doi.org/10.1016/j.toxrep.2020.11.005 |