Cargando…
Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells
Cadmium (Cd(2+)) is considered a human carcinogen as it causes oxidative stress and alters DNA repair responses. However, how Cd(2+) is taken up by cells remains unclear. We hypothesized that Cd(2+) could be transported into cells via a membrane copper (Cu) transporter, CTR1. CTR1 expression was not...
Autores principales: | Kwok, Man Long, Li, Zhen Ping, Law, Tin Yu Samuel, Chan, King Ming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695923/ https://www.ncbi.nlm.nih.gov/pubmed/33294387 http://dx.doi.org/10.1016/j.toxrep.2020.11.005 |
Ejemplares similares
-
Oxidative stress and apoptotic effects of copper and cadmium in the zebrafish liver cell line ZFL
por: Kwok, Man Long, et al.
Publicado: (2020) -
Cadmium Impairs p53 Activity in HepG2 Cells
por: Urani, C., et al.
Publicado: (2014) -
Copper-Dependent Trafficking of the Ctr4-Ctr5 Copper Transporting Complex
por: Ioannoni, Raphaël, et al.
Publicado: (2010) -
Curcumin Effect on Copper Transport in HepG2 Cells
por: Berzina, Anita, et al.
Publicado: (2018) -
Impact of Cadmium on Intracellular Zinc Levels in HepG2 Cells: Quantitative Evaluations and Molecular Effects
por: Urani, Chiara, et al.
Publicado: (2015)