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Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis
Hepatocellular carcinoma (HCC) is a deadly form of liver malignancy with limited treatment options. Amplification and/or overexpression of c-MYC is one of the most frequent genetic events in human HCC. The mammalian target of Rapamycin Complex 1 (mTORC1) is a major functional axis regulating various...
Autores principales: | Jia, Jiaoyuan, Che, Li, Cigliano, Antonio, Wang, Xue, Peitta, Graziella, Tao, Junyan, Zhong, Sheng, Ribback, Silvia, Evert, Matthias, Chen, Xin, Calvisi, Diego F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696085/ https://www.ncbi.nlm.nih.gov/pubmed/33187130 http://dx.doi.org/10.3390/ijms21228467 |
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