Inhibitory Action of Antidiabetic Drugs on the Free Radical Production by the Rod Outer Segment Ectopic Aerobic Metabolism

Rod outer segments (OS) express the F(o)F(1)-ATP synthase and the respiratory chain, conducting an ectopic aerobic metabolism that produces free radicals in vitro. Diabetic retinopathy, a leading cause of vision loss, is associated with oxidative stress in the outer retina. Since metformin and glibe...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravera, Silvia, Caicci, Federico, Degan, Paolo, Maggi, Davide, Manni, Lucia, Puddu, Alessandra, Nicolò, Massimo, Traverso, Carlo E., Panfoli, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696108/
https://www.ncbi.nlm.nih.gov/pubmed/33203090
http://dx.doi.org/10.3390/antiox9111133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696108/
https://www.ncbi.nlm.nih.gov/pubmed/33203090
http://dx.doi.org/10.3390/antiox9111133

Ejemplares similares