Role of Conserved Residues and F322 in the Extracellular Vestibule of the Rat P2X7 Receptor in Its Expression, Function and Dye Uptake Ability

Activation of the P2X7 receptor results in the opening of a large pore that plays a role in immune responses, apoptosis, and many other physiological and pathological processes. Here, we investigated the role of conserved and unique residues in the extracellular vestibule connecting the agonist-bind...

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Detalles Bibliográficos
Autores principales: Rupert, Marian, Bhattacharya, Anirban, Stillerova, Vendula Tvrdonova, Jindrichova, Marie, Mokdad, Audrey, Boué-Grabot, Eric, Zemkova, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696158/
https://www.ncbi.nlm.nih.gov/pubmed/33182845
http://dx.doi.org/10.3390/ijms21228446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696158/
https://www.ncbi.nlm.nih.gov/pubmed/33182845
http://dx.doi.org/10.3390/ijms21228446

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