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Photoproducts of the Photodynamic Therapy Agent Verteporfin Identified via Laser Interfaced Mass Spectrometry

Verteporfin, a free base benzoporphyrin derivative monoacid ring A, is a photosensitizing drug for photodynamic therapy (PDT) used in the treatment of the wet form of macular degeneration and activated by red light of 689 nm. Here, we present the first direct study of its photofragmentation channels...

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Detalles Bibliográficos
Autores principales: Furlan, Chris, Berenbeim, Jacob A., Dessent, Caroline E. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696214/
https://www.ncbi.nlm.nih.gov/pubmed/33198255
http://dx.doi.org/10.3390/molecules25225280