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Whole Exome Sequence Analysis Provides Novel Insights into the Genetic Framework of Childhood-Onset Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) describes a rare, progressive vascular disease caused by the obstruction of pulmonary arterioles, typically resulting in right heart failure. Whilst PAH most often manifests in adulthood, paediatric disease is considered to be a distinct entity with increased mo...

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Detalles Bibliográficos
Autores principales:	Gelinas, Simone M., Benson, Clare E., Khan, Mohammed A., Berger, Rolf M. F., Trembath, Richard C., Machado, Rajiv D., Southgate, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696319/ https://www.ncbi.nlm.nih.gov/pubmed/33187088 http://dx.doi.org/10.3390/genes11111328

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