TLR2 Deficiency Exacerbates Imiquimod-Induced Psoriasis-Like Skin Inflammation through Decrease in Regulatory T Cells and Impaired IL-10 Production

Emerging evidence has demonstrated that Toll-like receptors (TLRs) are associated with autoimmune diseases. In this study, we investigated the role of TLR2 in psoriasis using imiquimod-induced psoriasis-like dermatitis. Although TLR2 signaling is known to play a critical role in the induction of pro...

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Detalles Bibliográficos
Autores principales: Nakao, Momoko, Sugaya, Makoto, Fujita, Hideki, Miyagaki, Tomomitsu, Morimura, Sohshi, Shibata, Sayaka, Asano, Yoshihide, Sato, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696365/
https://www.ncbi.nlm.nih.gov/pubmed/33202847
http://dx.doi.org/10.3390/ijms21228560

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