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Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property

Despite the fact that various reports have been discussing bone tissue regeneration, precise bone tissue manipulation, such as controlling the physical properties of the regenerated bone tissue, still remains a big challenge. Here, we focused on the teleost fish ribs showing flexible and tough mecha...

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Autores principales: Jiao, Yu Yang, Okada, Masahiro, Hara, Emilio Satoshi, Xie, Shi Chao, Nagaoka, Noriyuki, Nakano, Takayoshi, Matsumoto, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696420/
https://www.ncbi.nlm.nih.gov/pubmed/33198178
http://dx.doi.org/10.3390/ma13225099
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author Jiao, Yu Yang
Okada, Masahiro
Hara, Emilio Satoshi
Xie, Shi Chao
Nagaoka, Noriyuki
Nakano, Takayoshi
Matsumoto, Takuya
author_facet Jiao, Yu Yang
Okada, Masahiro
Hara, Emilio Satoshi
Xie, Shi Chao
Nagaoka, Noriyuki
Nakano, Takayoshi
Matsumoto, Takuya
author_sort Jiao, Yu Yang
collection PubMed
description Despite the fact that various reports have been discussing bone tissue regeneration, precise bone tissue manipulation, such as controlling the physical properties of the regenerated bone tissue, still remains a big challenge. Here, we focused on the teleost fish ribs showing flexible and tough mechanical properties to obtain a deeper insight into the structural and functional features of bone tissue from different species, which would be valuable for the superior design of bone-mimicking materials. Herein, we examined their compositions, microstructure, histology, and mechanical properties. The first rib of Carassius langsdorfii showed a higher Young’s modulus with a small region of chondrocyte clusters compared with other smaller ribs. In addition, highly oriented collagen fibers and osteocytes were observed in the first rib, indicating that the longest first rib would be more mature. Moreover, the layer-by-layer structure of the oriented bone collagen was observed in each rib. These microarchitectural and compositional findings of fish rib bone would give one the useful idea to reproduce such a highly flexible rib bone-like material.
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spelling pubmed-76964202020-11-29 Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property Jiao, Yu Yang Okada, Masahiro Hara, Emilio Satoshi Xie, Shi Chao Nagaoka, Noriyuki Nakano, Takayoshi Matsumoto, Takuya Materials (Basel) Article Despite the fact that various reports have been discussing bone tissue regeneration, precise bone tissue manipulation, such as controlling the physical properties of the regenerated bone tissue, still remains a big challenge. Here, we focused on the teleost fish ribs showing flexible and tough mechanical properties to obtain a deeper insight into the structural and functional features of bone tissue from different species, which would be valuable for the superior design of bone-mimicking materials. Herein, we examined their compositions, microstructure, histology, and mechanical properties. The first rib of Carassius langsdorfii showed a higher Young’s modulus with a small region of chondrocyte clusters compared with other smaller ribs. In addition, highly oriented collagen fibers and osteocytes were observed in the first rib, indicating that the longest first rib would be more mature. Moreover, the layer-by-layer structure of the oriented bone collagen was observed in each rib. These microarchitectural and compositional findings of fish rib bone would give one the useful idea to reproduce such a highly flexible rib bone-like material. MDPI 2020-11-12 /pmc/articles/PMC7696420/ /pubmed/33198178 http://dx.doi.org/10.3390/ma13225099 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jiao, Yu Yang
Okada, Masahiro
Hara, Emilio Satoshi
Xie, Shi Chao
Nagaoka, Noriyuki
Nakano, Takayoshi
Matsumoto, Takuya
Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property
title Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property
title_full Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property
title_fullStr Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property
title_full_unstemmed Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property
title_short Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property
title_sort micro-architectural investigation of teleost fish rib inducing pliant mechanical property
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696420/
https://www.ncbi.nlm.nih.gov/pubmed/33198178
http://dx.doi.org/10.3390/ma13225099
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