Genome-Scale Metabolic Modeling Reveals Metabolic Alterations of Multidrug-Resistant Acinetobacter baumannii in a Murine Bloodstream Infection Model

Multidrug-resistant (MDR) Acinetobacter baumannii is a critical threat to human health globally. We constructed a genome-scale metabolic model iAB5075 for the hypervirulent, MDR A. baumannii strain AB5075. Predictions of nutrient utilization and gene essentiality were validated using Biolog assay an...

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Detalles Bibliográficos
Autores principales: Zhao, Jinxin, Zhu, Yan, Han, Jiru, Lin, Yu-Wei, Aichem, Michael, Wang, Jiping, Chen, Ke, Velkov, Tony, Schreiber, Falk, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696501/
https://www.ncbi.nlm.nih.gov/pubmed/33207684
http://dx.doi.org/10.3390/microorganisms8111793

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