Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by aberrant amyloid-β (Aβ) and hyperphosphorylated tau aggregation. We have previously investigated the involvement of SEPTIN family members in AD-related cellular processes and discovered a role for SEPTIN8 in the sorting and acc...

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Detalles Bibliográficos
Autores principales: Marttinen, Mikael, Ferreira, Catarina B., Paldanius, Kaisa M. A., Takalo, Mari, Natunen, Teemu, Mäkinen, Petra, Leppänen, Luukas, Leinonen, Ville, Tanigaki, Kenji, Kang, Gina, Hiroi, Noboru, Soininen, Hilkka, Rilla, Kirsi, Haapasalo, Annakaisa, Hiltunen, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696542/
https://www.ncbi.nlm.nih.gov/pubmed/33203136
http://dx.doi.org/10.3390/cells9112482

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