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Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

Brown adipocytes store metabolic energy as triglycerides (TGs) in lipid droplets (LDs). Fatty acids released from brown adipocyte LDs by lipolysis are thought to activate and fuel UCP1-mediated thermogenesis. Here, we test this hypothesis by preventing fatty acid storage in murine brown adipocytes t...

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Detalles Bibliográficos
Autores principales: Chitraju, Chandramohan, Fischer, Alexander W., Farese, Robert V., Walther, Tobias C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696656/
https://www.ncbi.nlm.nih.gov/pubmed/33147469
http://dx.doi.org/10.1016/j.celrep.2020.108348

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