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Modeling Parkinson’s Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers

The accumulation of aggregated α-synuclein (αSyn) is a hallmark of Parkinson’s disease (PD). Current evidence indicates that small soluble αSyn oligomers (αSynOs) are the most toxic species among the forms of αSyn aggregates, and that size and topological structural properties are crucial factors fo...

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Detalles Bibliográficos
Autores principales:	Boi, Laura, Pisanu, Augusta, Palmas, Maria Francesca, Fusco, Giuliana, Carboni, Ezio, Casu, Maria Antonietta, Satta, Valentina, Scherma, Maria, Janda, Elzbieta, Mocci, Ignazia, Mulas, Giovanna, Ena, Anna, Spiga, Saturnino, Fadda, Paola, De Simone, Alfonso, Carta, Anna R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696693/ https://www.ncbi.nlm.nih.gov/pubmed/33198335 http://dx.doi.org/10.3390/ijms21228535

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