Cargando…

Tracing the Photoaddition of Pharmaceutical Psoralens to DNA

The psoralens 8-methoxypsoralen (8-MOP), 4,5′,8-trimethylpsoralen (TMP) and 5-methoxypsoralen (5-MOP) find clinical application in PUVA (psoralen + UVA) therapy. PUVA treats skin diseases like psoriasis and atopic eczema. Psoralens target the DNA of cells. Upon photo-excitation psoralens bind to the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diekmann, Janina, Theves, Isabell, Thom, Kristoffer A., Gilch, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696755/ https://www.ncbi.nlm.nih.gov/pubmed/33182821 http://dx.doi.org/10.3390/molecules25225242

Ejemplares similares

Natural Products From Sponges of the Genus Agelas - on the Trail of a [2+2]-Photoaddition Enzyme
por: Hao, Eleanor, et al.
Publicado: (2001)

Microflow photochemistry: UVC-induced [2 + 2]-photoadditions to furanone in a microcapillary reactor
por: Bachollet, Sylvestre, et al.
Publicado: (2013)

Psoralen-ultraviolet A treatment with Psoralen-ultraviolet B therapy in the treatment of psoriasis
por: Ahmed Asim, Sadaf, et al.
Publicado: (2013)

Formation and repair of psoralen-DNA adducts and pyrimidine dimers in human DNA and chromatin.
por: Cleaver, J E, et al.
Publicado: (1985)

Photoaddition reactions of N-benzylglycinates containing α-trimethylsilyl group with dimethyl acetylenedicarboxylate: competitive formation of pyrroles vs. β-enamino esters
por: Lim, Suk Hyun, et al.
Publicado: (2019)

Repair of interstrand cross-links in DNA induced by psoralen plus light.
por: Cole, R. S.
Publicado: (1973)

Effects of psoralen on the pharmacokinetics of anastrozole in rats
por: Zhang, Yuzhu, et al.
Publicado: (2018)

Processing of triplex-directed psoralen DNA interstrand crosslinks by recombination mechanisms
por: Liu, Yaobin, et al.
Publicado: (2008)

A Review of the Pharmacological Properties of Psoralen
por: Ren, Yali, et al.
Publicado: (2020)

Psoralen Derivatives as Inhibitors of Mycobacterium tuberculosis Proteasome
por: Rožman, Kaja, et al.
Publicado: (2020)

Design, Synthesis and Antifungal Activity of Psoralen Derivatives
por: Yu, Xiang, et al.
Publicado: (2017)

Pharmaceutical Trace Analysis
por: Aldrich, D. Scott, et al.
Publicado: (1988)

A method for genome-wide analysis of DNA helical tension by means of psoralen–DNA photobinding
por: Bermúdez, Ignacio, et al.
Publicado: (2010)

Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease
por: Christensen, Laura A., et al.
Publicado: (2008)

ERCC1–XPF targeting to psoralen–DNA crosslinks depends on XPA and FANCD2
por: Sabatella, Mariangela, et al.
Publicado: (2019)

Effects of psoriasis and psoralen exposure on the somatic mutation landscape of the skin
por: Olafsson, Sigurgeir, et al.
Publicado: (2023)

Physicochemical Investigation of Psoralen Binding to Double Stranded DNA through Electroanalytical and Cheminformatic Approaches
por: Thomaz, Douglas Vieira, et al.
Publicado: (2020)

Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells
por: Couvé-Privat, Sophie, et al.
Publicado: (2007)

X-Ray Psoralen Activated Cancer Therapy (X-PACT)
por: Oldham, Mark, et al.
Publicado: (2016)

Possible role of psoralen-induced phototoxicity in the development of vitiligo
por: Patrick, Genevieve, et al.
Publicado: (2022)

The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure
por: Martin, Peter R., et al.
Publicado: (2017)

Psoralen Derivatives: Recent Advances of Synthetic Strategy and Pharmacological Properties
por: Jamalis, Joazaizulfazli, et al.
Publicado: (2020)

Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens
por: Krishnan, Rajagopal, et al.
Publicado: (2010)

Mechanisms Underlying the Antiproliferative and Prodifferentiative Effects of Psoralen on Adult Neural Stem Cells via DNA Microarray
por: Ning, You, et al.
Publicado: (2013)

Cavamax W7 composite psoralen ethosomal gel versus cavamax W7 psoralen solid complex gel for topical delivery: A comparative evaluation
por: Kumari, Smriti, et al.
Publicado: (2013)

Femtosecond Spectroscopy on a Dibenzophenazine‐Cored Macrocycle Exhibiting Thermally Activated Delayed Fluorescence
por: Thom, Kristoffer A., et al.
Publicado: (2023)

Psoralen Induced Liver Injury by Attenuating Liver Regenerative Capability
por: Zhou, Wang, et al.
Publicado: (2018)

Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors
por: Schiffrer, Eva Shannon, et al.
Publicado: (2021)

Psoralen as a Photosensitizers for Photodynamic Therapy by Means of In Vitro Cherenkov Light
por: Hübinger, Lisa, et al.
Publicado: (2022)

In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies
por: Somani, Gauresh, et al.
Publicado: (2015)

Limited Effectiveness of Psoralen- and Ultraviolet-Inactivated Vaccinia Virus on SHIV Infection
por: Glenn, L. Lee
Publicado: (2013)

Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis
por: Zhang, Yong-Tai, et al.
Publicado: (2014)

Multiple Skin Cancers Following Psoralen and Ultraviolet A Treatment of Psoriasis
por: Kang, Jin Seok, et al.
Publicado: (2014)

Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives
por: Meleddu, Rita, et al.
Publicado: (2021)

The Human Oxidative DNA Glycosylase NEIL1 Excises Psoralen-induced Interstrand DNA Cross-links in a Three-stranded DNA Structure
por: Couvé, Sophie, et al.
Publicado: (2009)

Combination therapy with BMP-2 and psoralen enhances fracture healing in ovariectomized mice
por: Huang, Kui, et al.
Publicado: (2018)

Therapeutic effect of psoralen on muscle atrophy induced by tumor necrosis factor-α
por: Lin, Xin-Feng, et al.
Publicado: (2020)

Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds
por: Wang, Yi, et al.
Publicado: (2011)

The In Vitro Effect of Psoralen on Glioma Based on Network Pharmacology and Potential Target Research
por: Wu, Yang, et al.
Publicado: (2022)

Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks
por: Thoma, Brian S., et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_c3u2n1sn8aruvdj5ieo5b4cki3