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USP25 Regulates EGFR Fate by Modulating EGF-Induced Ubiquitylation Dynamics

Deregulated epidermal growth factor receptor (EGFR) signaling is a key feature in different stages of oncogenesis. One important mechanism whereby cancer cells achieve increased and uncontrolled EGFR signaling is escaping down-modulation of the receptor. Ubiquitylation of the EGFR plays a decisive r...

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Detalles Bibliográficos
Autores principales:	Niño, Carlos A., Wollscheid, Nadine, Giangreco, Giovanni, Maspero, Elena, Polo, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696865/ https://www.ncbi.nlm.nih.gov/pubmed/33202887 http://dx.doi.org/10.3390/biom10111548

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