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BH3 Mimetics for the Treatment of B-Cell Malignancies—Insights and Lessons from the Clinic

SIMPLE SUMMARY: B-cell malignancies, including chronic lymphocytic leukemia (CLL), non-Hodgkin lymphoma (NHL), and plasma cell dyscrasias, are significant contributors to cancer morbidity and mortality worldwide. The pathogenesis of many B-cell malignancies involves perturbations in the intrinsic pa...

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Detalles Bibliográficos
Autores principales: Lin, Victor S., Xu, Zhuo-Fan, Huang, David C. S., Thijssen, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696913/
https://www.ncbi.nlm.nih.gov/pubmed/33198338
http://dx.doi.org/10.3390/cancers12113353