Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers

This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitu...

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Autores principales: Sochorova, Lenka, Prusova, Bozena, Cebova, Martina, Jurikova, Tunde, Mlcek, Jiri, Adamkova, Anna, Nedomova, Sarka, Baron, Mojmir, Sochor, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696942/
https://www.ncbi.nlm.nih.gov/pubmed/33202575
http://dx.doi.org/10.3390/molecules25225311
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author Sochorova, Lenka
Prusova, Bozena
Cebova, Martina
Jurikova, Tunde
Mlcek, Jiri
Adamkova, Anna
Nedomova, Sarka
Baron, Mojmir
Sochor, Jiri
author_facet Sochorova, Lenka
Prusova, Bozena
Cebova, Martina
Jurikova, Tunde
Mlcek, Jiri
Adamkova, Anna
Nedomova, Sarka
Baron, Mojmir
Sochor, Jiri
author_sort Sochorova, Lenka
collection PubMed
description This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of “Vitis vinifera L.” seed extract reduce the level of oxidative stress and improve the overall lipid metabolism.
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spelling pubmed-76969422020-11-29 Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers Sochorova, Lenka Prusova, Bozena Cebova, Martina Jurikova, Tunde Mlcek, Jiri Adamkova, Anna Nedomova, Sarka Baron, Mojmir Sochor, Jiri Molecules Review This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of “Vitis vinifera L.” seed extract reduce the level of oxidative stress and improve the overall lipid metabolism. MDPI 2020-11-14 /pmc/articles/PMC7696942/ /pubmed/33202575 http://dx.doi.org/10.3390/molecules25225311 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sochorova, Lenka
Prusova, Bozena
Cebova, Martina
Jurikova, Tunde
Mlcek, Jiri
Adamkova, Anna
Nedomova, Sarka
Baron, Mojmir
Sochor, Jiri
Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers
title Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers
title_full Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers
title_fullStr Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers
title_full_unstemmed Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers
title_short Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers
title_sort health effects of grape seed and skin extracts and their influence on biochemical markers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696942/
https://www.ncbi.nlm.nih.gov/pubmed/33202575
http://dx.doi.org/10.3390/molecules25225311
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