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From Target-Oriented to Motif-Oriented: A Case Study on Nannocystin Total Synthesis
Natural product total synthesis is in essence target-oriented in that a set of organic transformations are orchestrated into a workable process, leading ultimately to the target molecule with a predefined architecture. For a bioactive lead, proof of synthetic viability is merely the beginning. Ensui...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697126/ https://www.ncbi.nlm.nih.gov/pubmed/33203102 http://dx.doi.org/10.3390/molecules25225327 |