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NLRP3 Inflammasome Activation Is Involved in LPA(1)-Mediated Brain Injury after Transient Focal Cerebral Ischemia

Lysophosphatidic acid receptor 1 (LPA(1)) contributes to brain injury following transient focal cerebral ischemia. However, the mechanism remains unclear. Here, we investigated whether nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activ...

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Detalles Bibliográficos
Autores principales: Lee, Chi-Ho, Sapkota, Arjun, Gaire, Bhakta Prasad, Choi, Ji Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697439/
https://www.ncbi.nlm.nih.gov/pubmed/33202644
http://dx.doi.org/10.3390/ijms21228595