Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products

The revised Promotion Act, enforced in April 2020, allows the establishment of dedicated smoking rooms for heated tobacco products (HTPs). Since carcinogenicity assessment is unable to determine the safe level of secondhand smoke, we estimated excess lifetime cancer risk using previously reported ri...

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Detalles Bibliográficos
Autores principales: Hirano, Tomoyasu, Takei, Teiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697552/
https://www.ncbi.nlm.nih.gov/pubmed/33182793
http://dx.doi.org/10.3390/ijerph17228319
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author Hirano, Tomoyasu
Takei, Teiji
author_facet Hirano, Tomoyasu
Takei, Teiji
author_sort Hirano, Tomoyasu
collection PubMed
description The revised Promotion Act, enforced in April 2020, allows the establishment of dedicated smoking rooms for heated tobacco products (HTPs). Since carcinogenicity assessment is unable to determine the safe level of secondhand smoke, we estimated excess lifetime cancer risk using previously reported risk factors. Assuming that nicotine inhalation is proportional to cancer potency, the lifetime cancer risk for HTP IQOS is expected to be below 10(−5) (1/100,000), which is three orders of magnitude lower than that for cigarettes.
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spelling pubmed-76975522020-11-29 Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products Hirano, Tomoyasu Takei, Teiji Int J Environ Res Public Health Brief Report The revised Promotion Act, enforced in April 2020, allows the establishment of dedicated smoking rooms for heated tobacco products (HTPs). Since carcinogenicity assessment is unable to determine the safe level of secondhand smoke, we estimated excess lifetime cancer risk using previously reported risk factors. Assuming that nicotine inhalation is proportional to cancer potency, the lifetime cancer risk for HTP IQOS is expected to be below 10(−5) (1/100,000), which is three orders of magnitude lower than that for cigarettes. MDPI 2020-11-10 2020-11 /pmc/articles/PMC7697552/ /pubmed/33182793 http://dx.doi.org/10.3390/ijerph17228319 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Hirano, Tomoyasu
Takei, Teiji
Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products
title Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products
title_full Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products
title_fullStr Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products
title_full_unstemmed Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products
title_short Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products
title_sort estimating the carcinogenic potency of second-hand smoke and aerosol from cigarettes and heated tobacco products
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697552/
https://www.ncbi.nlm.nih.gov/pubmed/33182793
http://dx.doi.org/10.3390/ijerph17228319
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