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Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer

SIMPLE SUMMARY: Colorectal cancer is the third most common cause of cancer-related deaths. The Wnt signaling pathway is activated by genetic mutations in most patients with colorectal cancer. A number of different types of Wnt pathway mutation have been described: some increase the sensitivity of tu...

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Detalles Bibliográficos
Autores principales: Kleeman, Sam O., Leedham, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697568/
https://www.ncbi.nlm.nih.gov/pubmed/33202731
http://dx.doi.org/10.3390/cancers12113355