Cargando…
Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer
SIMPLE SUMMARY: Colorectal cancer is the third most common cause of cancer-related deaths. The Wnt signaling pathway is activated by genetic mutations in most patients with colorectal cancer. A number of different types of Wnt pathway mutation have been described: some increase the sensitivity of tu...
Autores principales: | Kleeman, Sam O., Leedham, Simon J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697568/ https://www.ncbi.nlm.nih.gov/pubmed/33202731 http://dx.doi.org/10.3390/cancers12113355 |
Ejemplares similares
-
WNT Ligand Dependencies in Pancreatic Cancer
por: Aguilera, Kristina Y., et al.
Publicado: (2021) -
Emerging Roles of Wnt Ligands in Human Colorectal Cancer
por: Nie, Xiaobo, et al.
Publicado: (2020) -
Wnt ligand–dependent activation of the negative feedback regulator Nkd1
por: Larraguibel, Jahdiel, et al.
Publicado: (2015) -
The Roles of Secreted Wnt Ligands in Cancer
por: Werner, Johannes, et al.
Publicado: (2023) -
Diffusion and function of Wnt ligands
por: Stewart, Richard A., et al.
Publicado: (2019)