Integrated Single-Cell RNA-Sequencing Analysis of Aquaporin 5-Expressing Mouse Lung Epithelial Cells Identifies GPRC5A as a Novel Validated Type I Cell Surface Marker

Molecular and functional characterization of alveolar epithelial type I (AT1) cells has been challenging due to difficulty in isolating sufficient numbers of viable cells. Here we performed single-cell RNA-sequencing (scRNA-seq) of tdTomato(+) cells from lungs of AT1 cell-specific Aqp5-Cre-IRES-DsRe...

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Detalles Bibliográficos
Autores principales: Horie, Masafumi, Castaldi, Alessandra, Sunohara, Mitsuhiro, Wang, Hongjun, Ji, Yanbin, Liu, Yixin, Li, Fan, Wilkinson, Thomas A., Hung, Long, Shen, Hua, Kage, Hidenori, Offringa, Ite A., Marconett, Crystal N., Flodby, Per, Zhou, Beiyun, Borok, Zea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697677/
https://www.ncbi.nlm.nih.gov/pubmed/33187367
http://dx.doi.org/10.3390/cells9112460

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