Monitoring Methylmalonic Aciduria by NMR Urinomics

The paper reports on monitoring methylmalonic aciduria (MMA)-specific and non-specific metabolites via NMR urinomics. Five patients have been monitored over periods of time; things involved were diet, medication and occasional episodes of failing to comply with prescribed diets. An extended dataset...

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Autores principales: Nicolescu, Alina, Blanita, Daniela, Boiciuc, Chiril, Hlistun, Victoria, Cristea, Mihaela, Rotaru, Dorina, Pinzari, Ludmila, Oglinda, Ana, Stamati, Adela, Tarcomnicu, Isabela, Tutulan-Cunita, Andreea, Stambouli, Danae, Gladun, Sergiu, Revenco, Ninel, Uşurelu, Natalia, Deleanu, Calin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697698/
https://www.ncbi.nlm.nih.gov/pubmed/33202577
http://dx.doi.org/10.3390/molecules25225312
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author Nicolescu, Alina
Blanita, Daniela
Boiciuc, Chiril
Hlistun, Victoria
Cristea, Mihaela
Rotaru, Dorina
Pinzari, Ludmila
Oglinda, Ana
Stamati, Adela
Tarcomnicu, Isabela
Tutulan-Cunita, Andreea
Stambouli, Danae
Gladun, Sergiu
Revenco, Ninel
Uşurelu, Natalia
Deleanu, Calin
author_facet Nicolescu, Alina
Blanita, Daniela
Boiciuc, Chiril
Hlistun, Victoria
Cristea, Mihaela
Rotaru, Dorina
Pinzari, Ludmila
Oglinda, Ana
Stamati, Adela
Tarcomnicu, Isabela
Tutulan-Cunita, Andreea
Stambouli, Danae
Gladun, Sergiu
Revenco, Ninel
Uşurelu, Natalia
Deleanu, Calin
author_sort Nicolescu, Alina
collection PubMed
description The paper reports on monitoring methylmalonic aciduria (MMA)-specific and non-specific metabolites via NMR urinomics. Five patients have been monitored over periods of time; things involved were diet, medication and occasional episodes of failing to comply with prescribed diets. An extended dataset of targeted metabolites is presented, and correlations with the type of MMA are underlined. A survey of previous NMR studies on MMA is also presented.
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spelling pubmed-76976982020-11-29 Monitoring Methylmalonic Aciduria by NMR Urinomics Nicolescu, Alina Blanita, Daniela Boiciuc, Chiril Hlistun, Victoria Cristea, Mihaela Rotaru, Dorina Pinzari, Ludmila Oglinda, Ana Stamati, Adela Tarcomnicu, Isabela Tutulan-Cunita, Andreea Stambouli, Danae Gladun, Sergiu Revenco, Ninel Uşurelu, Natalia Deleanu, Calin Molecules Article The paper reports on monitoring methylmalonic aciduria (MMA)-specific and non-specific metabolites via NMR urinomics. Five patients have been monitored over periods of time; things involved were diet, medication and occasional episodes of failing to comply with prescribed diets. An extended dataset of targeted metabolites is presented, and correlations with the type of MMA are underlined. A survey of previous NMR studies on MMA is also presented. MDPI 2020-11-14 /pmc/articles/PMC7697698/ /pubmed/33202577 http://dx.doi.org/10.3390/molecules25225312 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nicolescu, Alina
Blanita, Daniela
Boiciuc, Chiril
Hlistun, Victoria
Cristea, Mihaela
Rotaru, Dorina
Pinzari, Ludmila
Oglinda, Ana
Stamati, Adela
Tarcomnicu, Isabela
Tutulan-Cunita, Andreea
Stambouli, Danae
Gladun, Sergiu
Revenco, Ninel
Uşurelu, Natalia
Deleanu, Calin
Monitoring Methylmalonic Aciduria by NMR Urinomics
title Monitoring Methylmalonic Aciduria by NMR Urinomics
title_full Monitoring Methylmalonic Aciduria by NMR Urinomics
title_fullStr Monitoring Methylmalonic Aciduria by NMR Urinomics
title_full_unstemmed Monitoring Methylmalonic Aciduria by NMR Urinomics
title_short Monitoring Methylmalonic Aciduria by NMR Urinomics
title_sort monitoring methylmalonic aciduria by nmr urinomics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697698/
https://www.ncbi.nlm.nih.gov/pubmed/33202577
http://dx.doi.org/10.3390/molecules25225312
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